THIAMINE (VITAMIN B₁)

Vitamin B

Dosage Forms

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Tablet

100 mg

Injection

100 mg/ml

Uses

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  • Thiamine deficiency
  • Beriberi
  • Wernicke’s encephalopathy (specialist use only)

Dose and Duration

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Mild deficiency

Adult and child over 3 years: 25‒100 mg PO daily.

Severe deficiency

Adult and child over years: 200‒300 mg PO daily in divided doses, OR by IV infusion over 30 minutes.

Wernicke’s encephalopathy (specialist use)

Adult and child over years: by slow IV injection over 10 minutes, 300 mg daily in divided doses.

Side Effects

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  • Anaphylaxis following parenteral administration

Pregnancy

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  • Can be used.

Breast-feeding

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  • Can be used.

⚠️ Caution

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  • Mothers with severe thiamine deficiency should not breast feed as toxic methyl-glyoxal is present in milk.