SURAMIN SODIUM

Adult: by slow IV injection, initially 3.3 mg/kg as a single test dose (inject a few microlitres and wait for at least 1 minute, then inject the next 0.5 ml over 30 seconds and wait for 1 minute, then inject the remainder over several minutes), followed by incremental doses at weekly intervals of 6.7 mg/kg, 10.0 mg/kg, 13.3 mg/kg, 16.7 mg/kg, and 16.7 mg/kg on weeks 2 to 6 respectively (total dose, 66.7 mg/kg over 6 weeks).

Adult and child: by slow IV injection, 5 mg/kg on day 1, 10 mg/kg on day 3, and 20 mg/kg on days 5, 11, 17, 23, and 30.