Tablet
50 mg
Dosage Forms
Uses
Dose and Duration
Oedema and ascites in liver cirrhosis
Adult: 100–400 mg daily, adjusted according to response.
Child 12–18 years: 50–100 mg daily in 1–2 divided doses; up to 9 mg/kg daily (max 400 mg daily) in resistant cases.
Child 1 month–12 years: 1–3 mg/kg daily in 1–2 divided doses; up to 9 mg/kg daily in resistant ascites.
Neonate: 1–2 mg/kg daily in 1–2 divided doses; up to 7 mg/kg daily in resistant ascites.
Malignant ascites
Adult: 100–200 mg once daily, increased to 400 mg once daily if required; maintenance dose adjusted to response.
Child and neonate: dose same as in cirrhosis.
Nephrotic syndrome
Adult: 100–200 mg once daily.
Child and neonate: dose same as in cirrhosis.
Congestive heart failure with oedema
Adult: 100 mg in single or divided doses. Dose ranges from 25 mg to 200 mg. Maintenance dose is determined according to response.
Child and neonate: dose same as in cirrhosis.
Moderate to severe heart failure
Adult: 25 mg once daily increased to 50 mg once daily according to response.
Child and neonate: dose same as in cirrhosis.
Resistant hypertension
Adult: 25 mg once daily.
Primary hyperaldosteronism in patients awaiting surgery
Adult: 100–400 mg daily; use lowest effective dose for long-term maintenance.