SODIUM THIOSULPHATE

Antidote for cyanide poisoning

Dosage Forms

Injection

250 mg/ml

Uses

  • Cyanide poisoning

Dose and Duration

Cyanide poisoning (after sodium nitrite)

Adult and child: by slow IV injection over about 10 minutes, 12.5 g followed by 6.25 g after 30 minutes if symptoms recur.

Child: 400 mg/kg (max 12.5 g) repeated in severe poisoning after 30 minutes.

Pregnancy

  • Can be used

Breast-feeding

  • Can be used