ROTAVIRUS VACCINE

Live attenuated vaccine containing rotavirus gastroenteritis human strain. Rotavirus vaccine is used in the routine immunisation of children

Dosage Forms

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Oral suspension

1.5 ml prefilled oral syringe

Uses

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  • Immunisation against rotavirus infection

Dose and Duration

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Give drops in the mouth

First dose: At 6 weeks of life

Second dose: At 10 weeks

Minimal time interval between doses is 4 weeks

Contra-indications

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  • Immunocompromised patients

Side Effects

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  • Mild, short-lived gastrointestinal symptoms (pain, diarrhoea, irritation)

Interactions

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  • Dexamethasone (reduced effect of vaccine)
  • Hydrocortisone (reduced effect of vaccine)
  • Prednisolone (reduced effect of vaccine)

Patient Instructions

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  • Dispose of the child's faeces properly as the virus spreads through the oral-faecal route
  • Wash hands thoroughly after changing the baby's nappies

Pregnancy

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  • Not applicable

Breast-feeding

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  • Not applicable

Storage

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  • Between 2–8°C. Do not freeze

⚠️ Caution

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  • Postpone immunisation in infants with acute gastroenteritis or serious febrile illness
  • Booster doses after the primary schedule are not recommended