RISPERIDONE

Adult and child over 12 years: 2 mg in 1–2 divided doses on day 1 increased on day 2 to 4 mg daily in 1–2 divided doses if required. Usual dose range 4–6 mg/day. Only use doses above 10 mg if potential benefit outweighs risk (max 16 mg/day)

Elderly: starting dose of 0.5 mg every 12 hours increased by increments of 1 mg/day to 1–2 mg every 12 hours

In renal and hepatic impairment: ½ adult dose, with slower titration

Adult: 2 mg once daily increased at intervals of at least 24 hours in dose increments of 1 mg/day (max 6 mg/day)

Child 12–18 years: initially 0.5 mg once daily adjusted in steps of 0.5–1 mg daily according to response. Usual dose 2.5 mg daily in 1–2 divided doses (max 6 mg daily)

Elderly: same dose as for schizophrenia above

Adult: 0.25 mg every 12 hours individually increased at intervals of at least 48 hours by increments of 0.5 mg/day to a usual optimal dose of 0.5 mg every 12 hours (max 1 mg every 12 hours) for a max of 6 weeks

Child 1–18 years ≥ 50 kg: initially, 0.5 mg once daily increased at intervals of at least 48 hours by 0.5 mg once daily if required. Optimum dose, 1 mg once daily. Dose range 0.5–1.5 mg once daily

Child 1–18 years ≤ 50 kg: initially 0.25 mg once daily increased by 0.25 mg at least after 48 hours, if required. Optimum dose 0.5 mg once daily. Usual dose range 0.25–0.75 mg once daily