Tablet
150 mg
Injection
25 mg/ml
Dosage Forms
Uses
Dose and Duration
Gastritis and peptic ulcer disease
By mouth,
Adult: 150 mg every 12 hours or 300 mg once daily at night for 4–8 weeks in benign gastric and duodenal ulceration, up to 6 weeks in chronic episodic dyspepsia, and up to 8 weeks in NSAID-associated ulceration (in duodenal ulcer 300 mg can be given every 12 hours for 4 weeks to achieve a higher healing rate)
By IM injection,
Adult: 50 mg every 6–8 hours
By slow IV injection,
Adult: 50 mg diluted to 20 ml and given over at least 2 minutes, may be repeated every 6–8 hours
Prophylaxis of NSAID-associated gastric or duodenal ulcer
Adult: 300 mg every 12 hours until completion of NSAIDs
Prophylaxis of stress ulceration
Adult: 50 mg every 8 hours by slow IV injection over at least 2 minutes, then adjusted to 150 mg every 12 hours by mouth when oral feeding commences
Reflux oesophagitis
Adult: by mouth, 150 mg every 12 hours or 300 mg once at night for up to 8–12 weeks as necessary, increased in moderate to severe disease to 600 mg daily in 2–4 divided doses for up to 12 weeks
Long-term treatment of healed gastro-oesophageal reflux disease
150 mg every 12 hours
All uses
By mouth,
Child 12–18 years: 150 mg every 12 hours or 300 mg once at night; increased if necessary to 300 mg every 12 hours or 150 mg every 6 hours for up to 12 weeks in moderate to severe gastritis
Child 3–12 years: 2–4 mg/kg (max 150 mg) every 12 hours, increased up to 5 mg/kg (max 300 mg) every 12 hours in severe gastritis
Child 6 months–3 years: 2–4 mg/kg every 12 hours
Child 1–6 months: 1 mg/kg every 8 hours (max 3 mg/kg every 8 hours)
Neonate: 2 mg/kg every 8 hours (max 3 mg/kg every 8 hours)
By slow IV injection,
Child 1 month–18 years: 1 mg/kg (max 50 mg) every 6–8 hours (may be given as an intermittent infusion at a rate of 25 mg/hour)
Neonate: 0.5–1 mg/kg every 6–8 hours