PYRIDOXINE (VITAMIN B₆)

Vitamin B₆ essential for the proper functioning of nerves

Dosage Forms

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Tablet

25 mg
50 mg

Uses

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  • Treatment of pyridoxine deficiency
  • Prevention and treatment of nerve pain in hands and legs due to isoniazid

Dose and Duration

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Pyridoxine deficiency

25–50 mg every 8 hours until deficiency resolves

Prevention of nerve pain due to isoniazid

Adult and child: 25 mg once daily

Child <5 kg: 5 mg once daily

Give for as long as isoniazid treatment continues

Treatment of nerve pain due to isoniazid

Adult: 50 mg every 8 hours

Child: 50 mg once daily

Take until symptoms resolve, then reduce dose to the preventive doses for as long as isoniazid treatment continues

Side Effects

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  • Nerve disturbances (on prolonged use)

Pregnancy

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  • Can be used

Breast-feeding

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  • Can be used

⚠️ Caution

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  • Give pyridoxine to children receiving isoniazid prophylaxis against tuberculosis
  • Do not use high doses for long periods. Change to prevention doses as soon as possible