Emulsion for Injection
10 mg/ml
Dosage Forms
Uses
Dose and Duration
Induction of anaesthesia
Adult under 55 years and child over 17 years: by slow IV injection or infusion, 1.5–2.5 mg/kg at a rate of 20–40 mg every 10 seconds until response
Adult over 55 years or debilitated: 1–1.5 mg/kg at a rate of 20 mg every 10 seconds until response by slow IV injection or IV infusion
Child 1 month–17 years: 2.5–4 mg/kg adjusted according to age, weight and response
Maintenance anaesthesia
Adult and child over 17 years: by IV infusion, 4–12 mg/kg/hour. By slow IV injection, 25–50 mg repeated according to response
Child 1 month–17 years: by IV infusion, 9–15 mg/kg/hour adjusted according to weight, age and response
Elderly and debilitated: by IV infusion, 3–6 mg/kg/hour or 25–50 mg by slow IV injection
Pregnancy: max 6 mg/kg/hour
Sedation of ventilated patients in intensive care
Adult and child over 16 years: by IV infusion, 0.3–4 mg/kg/hour adjusted according to response
Induction of sedation for surgical and diagnostic procedures
Adult and child over 17 years: initially by slow IV injection over 1–5 minutes, 0.5– 1 mg/kg, dose and rate of administration adjusted according to desired level of sedation and response
Child 1 month–17 years: 1–2 mg/kg by slow IV injection over 1–5 minutes adjusted according to response
Maintenance of sedation for surgical and diagnostic procedures
Adult and child over 17 years: by IV infusion, 1.5–4.5 mg/kg/hour, dose and rate of administration adjusted according to desired level of sedation and response. If rapid increase in sedation is required, give an additional 10–20 mg by slow IV injection
Child 1 month–17 years: by IV infusion, 1.5–9 mg/kg/hour (if rapid sedation required, add by slow IV injection, max 1 mg/kg)