Propantheline

Dosage Forms

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Tablet

15 mg

Uses

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Gastrointestinal disorders with smooth muscle spasms
Adult enuresis
Gustatory sweating

Dose and Duration

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All uses

Adult and child over 12 years: 15 mg every 8 hours at least 1 hour before meals and 30 mg at night (max 120 mg daily). Adjust dose according to response

Gastrointestinal disorders characterised by smooth muscle spasms

Child 1 month–12 years: 0.3 mg/kg (max 15 mg) every 6–8 hours at least 1 hour before food

Contraindications

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Myasthenia gravis
Paralytic ileus
Pyloric stenosis
Toxic megacolon
Intestinal atony
Prostatic enlargement
Hypersensitivity to propantheline

Side Effects

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Constipation
Transient bradycardia
Reduced bronchial secretions
Urinary urgency and retention
Dilatation of pupils, loss of accommodation, photophobia
Dry mouth
Flushing, dryness of skin

Patient Instructions

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Take your medicine at least 1 hour before meals
Do not drive or operate machinery if the medicine causes drowsiness or blurring of vision

Pregnancy

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Do not use

Breast-feeding

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Do not use

⚠️ Caution

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Propantheline may suppress lactation
Use with caution in Down’s syndrome, in children and the elderly, patients with diarrhoea, severe heart disease, ulcerative colitis and in gastrointestinal reflux disease