PROGUANIL

Antimalarial medicine. Tissue schizonticide

Dosage Forms

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Tablet

100 mg

Uses

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  • Malaria prophylaxis in non-immune visitors to malaria-endemic countries

Dose and Duration

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Malaria prophylaxis

Adult and child > 14 years: 200 mg once daily

Child 9–14 years: 150 mg once daily

Child 5–8 years: 100 mg once daily

Child 1–4 years: 50 mg once daily

Child < 1 year: 25 mg once daily

Start 1 week before entering endemic area and continue for 4 weeks after leaving

Side Effects

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  • Stomach upset, mouth ulcers
  • Hypersensitivity reactions

Patient Instructions

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  • Take after food
  • Side effects mild and usually go as treatment continues

Pregnancy

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  • Can be used

Breast-feeding

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  • Can be used

⚠️ Caution

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  • Pregnant women must be given adequate folate supplements while taking proguanil