MOLNUPIRAVIR

(a prodrug) is a ribonucleoside analogue that increases the number of mutations in viral RNA thus preventing multiplication of the virus.

Dosage Forms

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Capsule

200 mg

Uses

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  • Covid-19 disease

Dose and Duration

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Mild to moderate COVID-19 [with at least 1 risk factor for developing severe illness]

By Mouth

Adult: 800 mg twice daily for 5 days, treatment to be started as soon as possible after diagnosis and within 5 days of symptom onset

Side Effects

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  • Diarrhoea
  • Dizziness
  • Nausea + vomiting
  • Headache

Contra-indications

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  • In Pregnancy

Pregnancy

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  • Avoid—toxicity in animal studies

Breast-feeding

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  • Avoid during treatment and for 4 days after last treatment—

⚠️ Caution

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  • Females of child bearing potential should use effective contraception during treatment and for 4 days after last treatment