Tablet
10 mg
Dosage Forms
Uses
Dose and Duration
Stage 2 hypertension (with another antihypertensive)
Adult: 10 mg once daily (2.5–5 mg in cardiac decompensation or volume depletion). Usual maintenance dose is 20 mg once daily (max 80 mg once daily)
Child 12–18 years: 5 mg once daily increased to usual maintenance dose of 10–20 mg once daily (max 80mg once daily)
Child 6–12 years: 0.07 mg/kg (max 5 mg) once daily increased at intervals of 1–2 weeks up to a maximum of 0.6 mg/kg (max 40 mg once daily)
Heart failure
Adult and child > 12 years: 2.5 mg once daily increased by not more than 10 mg at intervals of 2 weeks or more, up to a maximum of 35 mg once daily if tolerated
Renal disease in hypertensive patients with type II diabetes
mellitus
Adult and child > 12 years: 2.5–5 mg once daily; increased as required up to maintenance dose of 10–20 mg once daily
Prophylaxis after myocardial infarction (see caution)
Adult: Systolic blood pressure ≥120 mmHg; 5 mg within 24 hours of onset, followed by 5 mg after 24 hours, then 10 mg after another 24 hours and then 10 mg once daily for 6 weeks. Systolic blood pressure 100–120 mmHg; 2.5 mg daily increased to maintenance dose of 5 mg once daily for 6 weeks