Lactulose

Dosage Forms

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3.1–3.7 g/5 ml

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Hepatic encephalopathy

Adult and child above 12 years: 30–50 ml every 8 hours.

Adjust dose to produce 2–3 soft stools per day

Constipation

Adult: 15 ml every 12 hours

Child 5–18 years: 5–20 ml every 12 hours

Child 1–5 years: 2.5–10 ml every 12 hours

Child 1 month–1 year: 2.5 ml every 12 hours

Adjust dose according to response

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Take with water, fruit juice or meals to reduce nausea
Lactulose solution may be taken diluted or undiluted
Swallow each dose of lactulose at once and should not be kept in the mouth for an extended period of time
Consult your doctor if constipation persists after 3 days

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Chronic use of unadjusted doses and misuse can result into diarrhoea and disturbances in electrolyte balance
The doses used in hepatic encephalopathy should be taken into consideration in diabetics. Doses used in constipation do not pose a problem to the diabetics
Defecation reflex may be disturbed during treatment in children