Powder for Injection
200 mg
Dosage Forms
Uses
Locally advanced or metastatic:
Dose and Duration
Bladder cancer (in combination with cisplatin)
1000 mg/m² by IV infusion over 30 minutes on day 1, 8 and 15 of
each 28-day cycle. Cycle repeated and dose reduced as necessary
Pancreatic cancer
1000 mg/m² by IV infusion over 30 minutes. Repeat once weekly
for up to 7 weeks followed by 1 week of rest. Repeat once weekly
for 3 consecutive weeks out of every 4 weeks.
Non-small cell lung cancer (monotherapy)
1000 mg/m² by IV infusion over 30 minutes. Repeat once weekly
for 3 weeks followed by a 1-week of rest. Repeat once weekly for
3 consecutive weeks out of every 4 weeks
Breast cancer (in combination with paclitaxel)
1250 mg/m² by IV infusion over 30 minutes (given after
paclitaxel infusion) on day 1 and 8 of each 21-day cycle. Cycle
repeated as necessary
Ovarian cancer (in combination with carboplatin)
1000 mg/m² by IV infusion over 30 minutes (given before
carboplatin infusion) on day 1 and 8 of each 21-day cycle. Cycle
repeated as necessary