DEXTRAN 70

Plasma expander solution. Expands and maintains blood volume in shock arising from conditions such as septicaemia and burns

Dosage Forms

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Solution for infusion

6%

Uses

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  • Short-term blood volume expansion

Dose and Duration

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Short term blood volume expansion
Adult:500‒1000 ml initially by rapid intravenous infusion, followed by a further 500 ml if necessary. Total dose should not exceed 20 ml/kg during the initial 24 hours. If needed, give 10 ml/kg daily for another 2 days. Do not use for longer than 3 days.
Child:20 ml/kg maximum

Contraindications

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  • Severe congestive heart failure
  • Kidney failure
  • Bleeding disorders e.g. thrombocytopenia

Side Effects

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  • Hypersensitivity reactions
  • Fever
  • Nasal congestion

Pregnancy

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  • Can be used

Breastfeeding

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  • Can be used

⚠️ Caution

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  • Can interfere with blood group cross matching and biochemical tests (take samples before start of infusion)
  • Do not use in conditions such as burns or peritonitis when there is loss of plasma protein, water and electrolytes over periods of several days. Use plasma or albumin solutions instead