Dose and duration will vary on tolerance of patient, size and
location of neoplasm and use of other forms of therapy. Dos es may
be reduced in case of concurrent or previous radiation and
chemotherapy
Wilms’ tumour
45 micrograms/kg by IV as per schedule by specialist
Rhabdomyosarcoma
15 micrograms/kg by IV daily for 5 days
Ewing’s sarcoma
1.25 mg/m² by IV as per schedule by specialist
Testicular carcinoma
1 mg/m² by IV as per schedule by specialist
Gestational trophoblastic neoplasia
12 micrograms/kg by IV daily for 5 days as a single agent;
OR 500 micrograms on days 1 and 2 in combination therapy
Metastatic melanoma
As per patient’s treatment schedule by specialist