Capsule
250 mg
Dosage Forms
Uses
Dose and Duration
Blood-cycloserine concentration should not exceed a peak of 30 mg/litre (measured 3–4 hours after dose)
MDR-TB (second-line; in combination with other medicines)
Adult and child over 12 years: initially 250 mg
every 12 hours for 14 days, increased according to blood
concentration and response up to max 500 mg every 12 hours
Child 2–12 years:3 initially 5 mg/kg(max 250
mg) every 12 hours for 14 days, adjusted according to response
and blood concentration up to max 10 mg/kg (max 500 mg) every 12
hours
Renal impairment:If creatinine clearance <50
ml/minute, increase dosing interval and monitor
blood-cycloserine concentration