Tablet
500 mg
Solution for IV infusion
2 mg/ml
Eye drops
0.3%
Dosage Forms
Uses
Dose and Duration
Urinary bladder infection
Adult: 500 mg single dose PO
Acute pyelonephritis
Adult:by mouth, 750 mg every 12 hours for 7–14
days
By IV infusion over 60 minutes, 400 mg every 8–12 hours
Brucellosis and typhoid fever
Adult: 500 mg every 12 hours for 14 days PO
In chronic typhoid fever, treat for 4–6 weeks
Pneumonia, anthrax
Adult:by mouth, 500 mg every 12 hours for 5
days
By IV infusion over 60 minutes, 400 mg every 12 hours
Bacterial dysentery (first line) and cholera
Adult:Bacterial dysentery (first line) and
cholera
Child:15 mg/kg every 12 hours for 3 days
Genital ulcer disease
Adult: 500 mg every 12 hours PO for 3 days
Prophylaxis of meningococcal meningitis
Adult: 500 mg single dose PO
Corneal ulcers
Adult and child over 1 year: day 1; apply 2
drops into the affected eye every 15 minutes for the first 6
hours and then 2 drops every 30 minutes during both day and
night time. Day 2; apply 2 drops in the affected eye every hour.
Days 3–14; apply 2 drops in the affected eye every 4 hours (max
duration of treatment 21 days)
Superficial ocular infection
Adult and child over 1 year: apply 1–2 drops 4
times a day; in severe infection apply every 2 hours during
waking hours for 2 days, then 4 times a day for 14 days (max
duration 21 days)