IV injection should be given slowly over 2–5 minutes. Give IV
infusion over 30–60 minutes in neonates
Meningitis (first line treatment)
Adult: 2 g IV or deep IM injection daily in 1
or 2 divided doses for 14 days
Child:50–100 mg/kg daily in 1 or 2 divided
doses for 14 days
Neonate: 20–50 mg/kg daily in 1 or 2 divided
doses (maximum 50 mg/kg) for 14 days
Septicaemia
Adult:2 g IV or deep IM injection daily in 1 or
2 divided doses for 10 days
Child: 50–100 mg/kg daily in 1 or 2 divided
doses for 10 days
Child 1-4 years: 100 mg once daily for 5−7 days
Neonate: 20–50 mg/kg daily in 1 or 2 divided
doses (max 50 mg/kg) for 10 days
Moderate to severe pneumonia (second line to ampicillin and
gentamicin)
Adult: 1–2 g IV or deep IM injection daily in 1
or 2 divided dose for 7 days
Child: 50 mg/kg daily in 1 or 2 divided doses
for 7 days
Neonate: 20–50 mg/kg daily in 1 or 2 divided
doses (max 50 mg/kg) for 7 days
Abnormal vaginal/urethral discharge syndrome (in combination
with metronidazole and doxycycline)
Adult: 1 g single dose by deep IM injection
Pelvic inflammatory disease; persistent urethral/vaginal
discharge syndrome
Adult:1 g once daily by deep IM injection for 3
days
Severe gonococcal infection
Adult:1 g by deep IM injection once daily for 7
days
Gonococcal eye infection in new born infant (in combination with
azithromycin)
25 mg/kg single dose by deep IM injection (max 125 mg)
Dysentery (second line for severely ill children)
50–80 mg/kg IV once daily for 3 days