Tablet
50 mg
Powder for injection
100 mg
Dosage Forms
Uses
Dose and Duration
Only use the IV route if oral route is not possible. Give IV injection over 1 minute followed by 50 ml sodium chloride intravenous infusion
Suppression of transplant rejection
Adult:by mouth or IV injection, up to 5 mg/kg
on the day of surgery, then reduced according to response to a
maintenance dose of 1–4 mg/kg per day or by IV infusion, 1–2.5
mg/kg/day adjusted according to response. Maintain therapy
indefinitely
Child 1 month–18 years: by mouth or IV infusion
maintenance dose of 1–3 mg/kg given 1–2 times a day, adjusted
according to response
Severe refractory eczema
Adult: by mouth, normal or high thiopurine
methyl transferase (TPMT) activity, 1–3 mg/kg per day:
intermediate TPMT activity, 0.5–1.5 mg/kg per day
Generalised myasthenia gravis (in conjunction with a steroid)
Adult: 0.5–1 mg/kg/day increased over 3–4 weeks
to 2.0 - 2.5 mg/kg/day
Child 1 month–18 years:by mouth, 1 mg/kg once a
day, adjusted according to response (max 3 mg/kg) Consider
withdrawal if there is no improvement within 3 months
Other conditions
Adult: by mouth or IV infusion, 1–3 mg/kg/day
adjusted according to response
Child 1 month–18 years:by mouth, 1 mg/kg once a
day, adjusted according to response (max 3 mg/kg) Consider
withdrawal if there is no improvement within 3 months