Injection
1 mg/ml
Eye drops
1%
Dosage Forms
Uses
Dose and Duration
Organophosphate poisoning
Adult: 2 mg IM or IV (according to the severity
of the poi soning)
Child: 20 micrograms/kg per dose
Repeat dose every 20‒30 minutes until signs of atropinisation occur (pupil dilatation, hot dry skin, dry mouth, fast pulse)
Premedication before anaesthesia
Adult: by IV injection; 300‒600 micrograms
immediately before induction of anaesthesia
Child: 20 micrograms/kg (maximum 600
micrograms)
OR
By SC or IM injection;
Adult: 300‒600 micrograms 30‒60 minutes before
induction of anaesthesia
Child:20 micrograms/kg (maximum 600 micrograms)
Intra-operative bradycardia (low heartbeat < 50 beats/minute)
Adult: 300‒600 micrograms (larger doses in
emergencies) by IV injection
Child 1‒12 years:10‒20 micrograms/kg by IV
injection
Control effects of neostigmine in reversal neuromuscular block
(specialist use only)
Adult and child >12 years: 600‒1200 micrograms
by IV injection
Neonate and child up to 12 years: 20
micrograms/kg by IV injection (max 600 micrograms)
Iritis, Uveitis
Adult: Apply 1 drop in the eyes every 6 hours
Child: Apply 1 drop in the eyes every 8 hours