AMPICILLIN + CLOXACILLIN

Combination of two broad spectrum penicillin antibiotics

Dosage Forms

▼

Powder for solution for injection

Ampicillin 250 mg + Cloxacillin 250 mg

Capsule

Ampicillin 250 mg + Cloxacillin 250 mg

Uses

▼
  • Post-operative wounds and skin infections
  • Pulmonary infections
  • Bronchopneumonia
  • Acute exacerbations of chronic bronchitis
  • Puerperal fever
  • Bacteraemia associated with or suspected to be associated with any of the infections above

Dose and Duration

▼
All uses
Give slow IV over 3–4 minutes for 5–14 days Adult and child over 10 years: 500–1000 mg every 6 hours by mouth OR 500–1000 mg every 4–6 hours by IV or IM injection
Child 2-10 years:250–500 mg every 6 hours OR 250-500 mg every 4–6 hours by IM or IV injection
Child < 2 years:250 mg every 6 hours by mouth OR 250 mg every 4–6 hours by IV/IM injection
Neonate:90 mg every 4 hours

Preparation

▼
  • For IM, dissolve 500 mg of powder in 1.5 ml of water for injection
  • For IV injection, dissolve 500 mg in 10 ml of water

→ For more information, see individual medicine monographs of ampicillin and cloxacillin