Slow IV injection given over 3–5 minutes or IV infusion given over
20–30 minutes
Severe meningitis
Adult: 3 g IV every 6 hours for 3 weeks (may be
given up to 6 weeks)
Child: 50 mg/kg (max 500 mg) every 6 hours for
3 weeks (may be given up to 6 weeks)
Neonatal meningitis and septicaemia (in combination with IV
gentamicin)
Treat for 7–10 days
Neonates >7 days:50 mg/kg every 8 hours
Neonates <7 days: 50 mg/kg every 12 hours
Severe pneumonia (first line for IMCI; in combination with IV
gentamicin)
Infant 1 week–2 months: 25–50 mg/kg every 8
hours for at least 5 days
Neonates <7 days: 25–50 mg/kg every 12 hours
for at least 5 days
Other uses
Adult: 2g IV every 6 hours for 10-14 days
Child:2g IV every 6 hours for 10-14 days