Tablet
100 mg
200 mg
Sterile concentrate:
50 mg/ml
Dosage Forms
Uses
Dose and Duration
Supraventricular and ventricular arrhythmias
➡️ By mouth
Adult and child above 12 years:200 mg every 8
hours for 1 week, then reduce to 200 mg every 12 hours for
another 1 week. Usual maintenance dose 200 mg once daily or
minimum required to control arrhythmia
Child 1 month–12 years: initially 5–10 mg/kg
(max 200 mg) every 12 hours for 7–10 days, then reduce to
maintenance dose of 5–10 mg/kg once a day (max 200 mg per day)
Neonate: initially 5–10 mg/kg every 12 hours
for 7–10 days, then reduce to maintenance dose of 5–10 mg/kg
once a day
➡️ By IV infusion
Adult:
initially 5 mg/kg over 20–120 minutes while monitoring ECG. Give
subsequent infusion if required depend ing on response up to max
1200 mg in 24 hours
Child 1 month–18 years:
initially 5–10 mg/kg over 20 minutes–2 hours then by continuous
infusion 0.3 mg/kg/hour, increased according to response to maxi
mum dose of 1.5 mg/kg/hour (max 1200 mg in 24 hours)
Neonate:
initially 5 mg/kg over 30 minutes then 5 mg/kg over 30 minutes
every 12–24 hours
Ventricular fibrillation and pulseless ventricular tachycardia
in cardiac arrest refractory to defibrillation (with
epinephrine)
Adult: by IV injection, initially 300 mg
(diluted in 20 ml glucose 5%). An additional dose of 150 mg by
IV injection can be given if required after at least 15 minutes,
followed by an IV infusion of 900 mg over 24 hours
Child 1 month–18 years: 5 mg/kg (max 300 mg)
over at least 3 minutes
Neonate: 5 mg/kg over at least 3 minutes