Tablet
100 mg
Dosage Forms
Uses
Dose and Duration
Prophylaxis of gout, hyperuricaemic nephropathy, over production
of urate
Adult: initially 100 mg daily after food; then
increase by 100 mg weekly according to plasma or urinary uric
acid levels to a daily maintenance dose of 100–900 mg (mild
conditions 100–200 mg daily, in moderate conditions 300–600 mg
daily, in severe conditions 700–900 mg dai ly). Give doses above
300 mg in divided doses
Prophylaxis of hyperuricaemia associated with cancer
Adult: Maintenance doses same as above. Adjust
dose according to response. Start treatment 24 hours before
chemotherapy and continue for 7–10 days there after
Child 1 month–15 years: 10–20 mg/kg daily (max
400 mg per day) after food
Note: In moderate renal impairment, reduce dose
to100 200 mg; in severe renal impairment, use maximum 100 mg
daily